





NeuroPure by Pure Encapsulations® – Mood Balance, Neurotransmitter & Migraine Support | 120 Vegetable Capsules
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Description
Support emotional balance, healthy neurotransmitter function and neurological wellness with NeuroPure by Pure Encapsulations®. This specialized formula combines 5-HTP, DL-phenylalanine, activated B vitamins, zinc, quercetin and Meriva® turmeric phytosome to support healthy mood balance and help reduce migraine severity and duration when used preventively.
KEY BENEFITS
- Healthy Mood Balance: Provides nutrients involved in serotonin and dopamine production.
- Neurotransmitter Support: Contains 5-HTP and DL-phenylalanine, precursors involved in neurotransmitter synthesis.
- Migraine Prevention Support: Authorized in Canada to help reduce migraine severity and duration when taken prophylactically.
- Emotional Wellness: Supports normal neurological function and mood regulation.
- Activated Vitamin B6: Provides pyridoxal-5-phosphate (P5P), a cofactor involved in neurotransmitter metabolism.
- Active Folate: Contains Metafolin® L-5-MTHF, a biologically active form of folate.
- Antioxidant Support: Features quercetin and Meriva® turmeric phytosome.
- Nervous System Health: Supplies zinc and essential B-vitamin cofactors.
- Vegetarian Capsules: Convenient capsule format for daily supplementation.
- Practitioner-Developed Formula: Part of the PureSYNAPSE™ product line.
WHO IT’S IDEAL FOR
NeuroPure may be suitable for adults who:
- Want nutritional support for healthy mood balance
- Are seeking support for normal neurotransmitter function
- Experience migraines and are considering preventive nutritional supplementation
- Want a formula containing serotonin and dopamine precursors
- Prefer activated forms of vitamin B6 and folate
- Are interested in antioxidant support for neurological wellness
- Have been advised by a healthcare practitioner to use targeted mood-support nutrients
Important: NeuroPure contains ingredients that can interact with antidepressants, migraine medications and other drugs affecting serotonin or dopamine. Consult a healthcare practitioner before use, particularly if you take prescription medication.
NeuroPure is not a substitute for treatment of depression, anxiety disorders or other diagnosed neurological or psychiatric conditions.
WHAT IT IS / WHAT IT DOES
NeuroPure is a specialized nutritional supplement developed by Pure Encapsulations® in collaboration with Dr. James Greenblatt.
It belongs to the PureSYNAPSE™ product line, which focuses on nutritional support for neurological function.
The formula combines neurotransmitter precursors with vitamins, minerals and antioxidant compounds.
1. Supports Serotonin Production
NeuroPure contains 5-hydroxytryptophan (5-HTP), a compound involved in serotonin synthesis.
Serotonin is a neurotransmitter associated with mood regulation and several other physiological functions.
Although 5-HTP can serve as a serotonin precursor, evidence supporting its effectiveness for mood disorders remains limited.
2. Supports Dopamine Synthesis
DL-phenylalanine provides phenylalanine, an amino acid involved in the pathway leading to dopamine production.
Dopamine contributes to normal neurological functions, including motivation, movement and reward processing.
Providing a precursor does not necessarily increase dopamine levels or improve mood in every individual.
3. Provides Essential Neurotransmitter Cofactors
NeuroPure contains:
- Activated vitamin B6 (P5P)
- Metafolin® L-5-MTHF
- Zinc picolinate
These nutrients participate in normal amino acid metabolism and neurological function.
4. Supports Migraine Prevention
NeuroPure carries a Canadian natural health product indication for helping reduce migraine severity and duration when taken preventively.
It is intended for ongoing preventive use rather than immediate treatment of an active migraine attack.
5. Provides Antioxidant Support
Quercetin and Meriva® turmeric phytosome provide plant-derived compounds with antioxidant properties.
These ingredients complement the formula’s nutritional support for overall cellular health.
FEATURES
|
Feature |
Details |
|---|---|
|
Product |
NeuroPure |
|
Brand |
Pure Encapsulations® |
|
Product Line |
PureSYNAPSE™ |
|
Primary Purpose |
Mood Balance & Neurological Support |
|
Additional Indication |
Migraine Prophylaxis |
|
Key Ingredients |
5-HTP, DL-Phenylalanine, P5P, L-5-MTHF, Zinc, Quercetin & Turmeric |
|
Folate Form |
Metafolin® L-5-MTHF |
|
Vitamin B6 Form |
Pyridoxal-5-Phosphate |
|
Turmeric Complex |
Meriva® Turmeric Phytosome |
|
Capsule Type |
Vegetable Capsules |
|
Package Size |
120 Capsules |
|
NPN |
80049188 |
|
Allergen Information |
Contains Soy |
MEDICINAL INGREDIENTS
The manufacturer lists the following medicinal ingredients.
|
Medicinal Ingredient |
Amount |
|---|---|
|
DL-Phenylalanine (Free-Form) |
700 mg |
|
5-Hydroxytryptophan (5-HTP) |
100 mg |
|
Meriva® Turmeric Phytosome |
250 mg |
|
Quercetin |
100 mg |
|
Folate (as Metafolin® L-5-MTHF) |
500 mcg |
|
Zinc (as Zinc Picolinate) |
10 mg |
|
Vitamin B6 (as Pyridoxal-5-Phosphate) |
10 mg |
Meriva® Turmeric Phytosome: Contains turmeric (Curcuma longa) root extract in a phospholipid complex standardized to 18% curcuminoids.
Important: The supplied ingredient table does not explicitly establish whether these amounts are per capsule or per serving. Verify the current Supplement Facts or Canadian product label before calculating total daily intake.
5-HTP – Serotonin Precursor
5-HTP is an intermediate compound in the conversion of tryptophan to serotonin.
It is included to support healthy mood balance and neurotransmitter function.
Safety consideration: Combining 5-HTP with medications or supplements that increase serotonin can raise the risk of serotonin syndrome, a potentially serious condition.
DL-Phenylalanine – Dopamine Pathway Support
DL-phenylalanine contains two forms of phenylalanine.
L-phenylalanine participates in the body’s synthesis of tyrosine and catecholamine neurotransmitters, including dopamine.
Individuals with phenylketonuria (PKU) must avoid this product.
Metafolin® – Active Folate
Metafolin® provides L-5-methyltetrahydrofolate, an active form of folate.
Folate contributes to normal cellular function and processes involved in neurological health.
Activated Vitamin B6 – P5P
Pyridoxal-5-phosphate is the active coenzyme form of vitamin B6.
It supports normal amino acid metabolism, including reactions involved in neurotransmitter synthesis.
Zinc Picolinate
Zinc is an essential mineral involved in enzyme activity, cellular function and normal nervous system health.
Meriva® Turmeric Phytosome
Meriva® combines turmeric extract with phospholipids.
This formulation is designed to improve the absorption of certain curcuminoids compared with conventional turmeric extracts.
Quercetin
Quercetin is a naturally occurring flavonoid found in various fruits and vegetables.
It is included for its antioxidant properties.
NON-MEDICINAL INGREDIENTS
- Hydroxypropyl Methylcellulose
- Purified Water
Allergen Information: Contains Soy.
The Meriva® phospholipid complex may be relevant to the product’s soy allergen declaration.
Individuals with soy allergies should avoid this product unless a healthcare professional confirms it is appropriate.
Always refer to the current product packaging for complete ingredient and allergen information.
RECOMMENDED DOSE
Adults – General Health Support
Take 2 capsules once or twice daily, or as directed by a healthcare practitioner.
Adults – Healthy Mood Balance & Migraine Prevention
Take 2 capsules twice daily, or as directed by a healthcare practitioner.
Administration Instructions
- Take with food.
- Take a few hours before or after other medications or natural health products.
- Follow the recommended dosage.
- Consult a healthcare practitioner for use beyond 3 months.
How Long Does One Bottle Last?
Each bottle contains 120 vegetable capsules.
|
Daily Dosage |
Approximate Supply |
|---|---|
|
2 Capsules Daily |
60 Days |
|
4 Capsules Daily |
30 Days |
Important: Do not exceed the recommended dose. The higher-dose regimen is intended for the manufacturer’s specified mood-balance and migraine-prevention indications.
NEUROTRANSMITTER SUPPORT & EMOTIONAL WELLNESS
Neurotransmitters are chemical messengers that help nerve cells communicate.
Two neurotransmitters relevant to NeuroPure’s formulation are serotonin and dopamine.
Serotonin
Serotonin contributes to several physiological functions, including:
- Mood regulation
- Sleep-wake processes
- Appetite regulation
- Gastrointestinal function
Dopamine
Dopamine is involved in:
- Motivation
- Reward processing
- Movement
- Attention and other neurological functions
NeuroPure provides nutrients involved in the normal synthesis and metabolism of these neurotransmitters.
However, mood disorders are complex, and their causes cannot be reduced to a simple deficiency of serotonin or dopamine.
MIGRAINE PREVENTION SUPPORT
NeuroPure is authorized in Canada to help reduce the severity and duration of migraine headaches when taken prophylactically.
What Does Prophylactic Mean?
Prophylactic use means taking a product preventively rather than waiting until symptoms begin.
Important Distinction
NeuroPure is not an acute migraine medication.
It should not replace prescribed migraine treatments or emergency medical evaluation when needed.
Consult a healthcare practitioner if:
- Migraines are frequent or worsening
- Headaches interfere with daily activities
- You require frequent acute migraine medication
- Your headache pattern changes significantly
Seek urgent medical attention for a sudden, unusually severe headache or a headache accompanied by new neurological symptoms.
FAQ
What is NeuroPure by Pure Encapsulations®?
NeuroPure is a nutritional supplement formulated with neurotransmitter precursors, activated B vitamins, zinc and antioxidant compounds to support healthy mood balance and neurological function.
What is NeuroPure used for?
It is used for general health maintenance, healthy mood balance and preventive support for migraine severity and duration, according to its Canadian natural health product indications.
Does NeuroPure contain 5-HTP?
Yes. The formula contains 5-hydroxytryptophan, a precursor involved in serotonin synthesis.
Does NeuroPure support dopamine production?
NeuroPure contains DL-phenylalanine, which supplies an amino acid involved in the dopamine synthesis pathway.
This does not guarantee increased dopamine levels or improved mood.
Can NeuroPure help prevent migraines?
NeuroPure has a Canadian natural health product indication for helping reduce migraine severity and duration when taken preventively.
It is not intended to stop an active migraine attack.
Can I take NeuroPure with antidepressants?
Do not combine NeuroPure with antidepressants without consulting a healthcare practitioner.
Its 5-HTP content may interact with SSRIs, MAOIs and other serotonergic medications.
Is NeuroPure suitable for vegetarians?
It is supplied in vegetable capsules. However, it contains soy, and suitability should be assessed against your individual dietary requirements.
How many capsules should I take?
Adults are directed to take 2 capsules once or twice daily. For healthy mood balance and migraine prevention, the manufacturer recommends 2 capsules twice daily.
How long can I take NeuroPure?
Consult a healthcare practitioner for use beyond 3 months.
Does NeuroPure contain soy?
Yes. The manufacturer declares soy as an allergen.
Is NeuroPure safe during pregnancy?
No. The manufacturer advises against use during pregnancy or breastfeeding.
What is the NPN for NeuroPure?
NPN 80049188.
CAUTIONS / WARNINGS
DO NOT USE IF YOU:
- Are pregnant or breastfeeding
- Take levodopa
- Have phenylketonuria (PKU)
- Have scleroderma
- Have tardive dyskinesia
- Have a known allergy to soy or another ingredient
IMPORTANT SEROTONIN INTERACTION WARNING
NeuroPure contains 5-HTP, which may interact with medications and supplements that affect serotonin.
Consult a healthcare practitioner before use if taking:
- SSRIs or other antidepressants
- Monoamine oxidase inhibitors (MAOIs)
- Triptans or other migraine medications
- Tramadol or other serotonergic pain medications
- Dextromethorphan-containing cough and cold medications
- Certain anti-nausea medications
- St. John’s wort
- SAMe
- L-Tryptophan
- Other serotonergic supplements
Serotonin syndrome can be life-threatening. Seek immediate medical attention if you develop symptoms such as agitation, confusion, fever, heavy sweating, rapid heartbeat, muscle rigidity or tremors, particularly after combining serotonergic products.
CONSULT A HEALTHCARE PRACTITIONER BEFORE USE IF YOU:
- Take anticoagulants or antiplatelet medications
- Take antipsychotic medications
- Take carbidopa
- Follow a low-protein diet
- Have gallstones or bile duct obstruction
- Have stomach ulcers
- Have excess stomach acid
- Have a neurological or psychiatric condition
- Take any prescription medication
POSSIBLE SIDE EFFECTS
Some individuals may experience:
- Drowsiness
- Nausea
- Vomiting
- Diarrhea
- Abdominal discomfort
Exercise caution when driving, operating machinery or performing activities requiring mental alertness.
DISCONTINUE USE AND CONSULT A HEALTHCARE PRACTITIONER IF YOU EXPERIENCE:
- Skin changes
- Unusual weakness
- Oral ulcers
- Abdominal pain accompanied by severe muscle pain
- Persistent or worsening symptoms
FOLATE & VITAMIN B12
Folate supplementation can complicate recognition of vitamin B12 deficiency.
Consult a healthcare practitioner if you are concerned about your vitamin B12 status.
GENERAL PRECAUTIONS
- For adult use only.
- Take with food.
- Separate from medications and other natural health products by a few hours.
- Consult a healthcare practitioner for use beyond 3 months.
- Do not exceed the recommended dose.
- Keep out of reach of children.
- Store according to the current product label.
LEGAL DISCLAIMER
Actual product packaging and materials may contain more and different information than what is shown on our website. We recommend that you do not rely solely on the information presented and that you always read labels, warnings, and directions before using or consuming a product.
NeuroPure by Pure Encapsulations® is a mood balance and neurotransmitter support supplement featuring 5-HTP, DL-phenylalanine, activated vitamin B6, Metafolin® L-5-MTHF, zinc, quercetin and Meriva® turmeric phytosome. Developed as part of the PureSYNAPSE™ product line, NeuroPure supports normal neurological function and is authorized in Canada to help reduce migraine severity and duration when taken preventively. Available in 120 vegetable capsules, this formula is intended for adults and should be used according to the product label, particularly when taking antidepressants or migraine medications. NPN 80049188.

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