AcaciaPlus® | Metagenics® | 90 Tablets



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Selective Kinase Response Modulators for Healthy Insulin Function* 

Formerly Insinase®

AcaciaPlus® (Insinase®) is a nutritional supplement with scientifically tested ingredients designed to support healthy insulin function. Developed through the ExpresSyn® Process, AcaciaPlus® provides selective kinase response modulators (SKRMs) in the forms of reduced iso-alpha acids (RIAA) and Acacia nilotica. Kinases play an important role in healthy insulin signaling and overall insulin function.*


  • Proprietary formula featuring SKRMs—RIAA and acacia—which have been shown to modulate insulin function.
  • SKRMs modulate kinase signaling in adipocytes, which are fat-storing cells involved in glucose utilization and insulin signaling.
  • Balanced kinase signaling may help to maintain healthy glucose and triglyceride regulation.
  • In vitro testing of the active ingredients has demonstrated inhibition of IL-6 cytokines—which influence insulin function

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Label & Supplement Facts


Serving size: 3 Tablets
Servings Per Container: 30

Ingredients Amount Per Serving % Daily Value
Serving Size 3 Tablets  
Servings Per Container 30  
Total Carbohydratet <1 g <1%*
Dietary Fiber <1 g 3%*
Proprietary Blend of:
   Reduced Iso-Alpha Acids and Indian Gum Arabic Tree (Acacia nilotica) Bark and Heartwood Extract

540 mg 

Other Ingredients

Microcrystalline cellulose, cellulose, stearic acid (vegetable), croscarmellose sodium, sodium starch glycolate, silica, and coating [hypromellose, medium-chain triglycerides, hydroxypropylcellulose, and sodium copper chlorophyllin (color)].


Take three tablets daily or as directed by your healthcare practitioner.

This product is non-GMO, gluten-free, and vegetarian.

AcaciaPlus® by Metagenics is a natural supplement for insulin support that features selective kinase response modulators (SKRMs) RIAA and acacia which have been clinically shown in a preliminary study at the FMRC to improve fasting insulin and lipid parameters. 

  • Ground-breaking preliminary research suggests that SKRMs modulate kinase signals in favor of good health
  • Designed to modulate kinase signalling (within cells) in favor of healthy insulin function and blood sugar transport
  • Balanced kinase signalling helps to maintain healthy blood sugar and triglyceride regulation
  • Developed through the ExpresSyn Process - which combines proteomic research, safety evaluations, and human clinical research to set a new standard of clinical certainty in nutritional supplements.
  • Gluten-free
  • Vegetarian

FMRC (Functional Medicine Research CenterSM) is the clinical research arm of Metagenics.


Do not use if pregnant, nursing, or taking anticoagulants. If taking other medication, consult your healthcare practitioner before use. Keep out of the reach of children.

Tamper Evident

Do not use if safety seal is missing or broken.


Keep tightly closed in a cool, dry place.

*Percent Daily Values are based on a 2,000 calorie diet.

**Daily Value not established.

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