B12 Methylcobalamin 5000 mcg | Bioclinic® Naturals | 60 Sublingual Tablets

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Description

Vitamin B12 in its most bioactive form (Methylcobalamin 5000 mcg)

Vitamin B12 is the cofactor in enzymatic reactions with diverse physiological functions. It is required for the conversion of methylmalonyl CoA to succinyl CoA, as well as for the conversion of homocysteine to methionine by methionine synthase, which is then converted into S-adenosylmethionine.2 A B12 deficiency causes impairments in both of these pathways, disrupting neurological function, including poor formation of myelin nerve sheaths, production of toxic levels of homocysteine, and inefficient energy production in all cells.3,4 

Features

  • A B12 deficiency causes impairments in both of these pathways, disrupting neurological function, including poor formation of myelin nerve sheaths
  • Because of its relationship to myelin production and neurological function, high dose B12 has been used in a variety of neurodegenerative diseases
  • Some individuals, especially those with malabsorption or low dietary intake, are at higher risk for a B12 deficiency
  • B12 has been well established to increase cellular levels of glutathione, the most prevalent intercellular antioxidant

Methylcobalamin, the principal circulating form of B12 and the one transported into peripheral tissues, has been shown to not only reduce homocysteine, but also to reduce inflammatory factors and the volume of carotid artery plaques among stroke patients, as well as pain, and neuropathy among diabetics.5-8 Because of its relationship to myelin production and neurological function, high dose B12 has been used in a variety of neurodegenerative diseases, including Parkinson’s disease, amyotrophic lateral sclerosis, and multiple sclerosis.9–12

Some individuals, especially those with malabsorption or low dietary intake, are at higher risks for a B12 deficiency. Individuals with impaired absorption of B12 rely on passive absorption, which is typically 1% of the ingested amount. Thus, high doses may be required for those with greater B12 needs, such as elderly individuals and those with neurodegenerative disorders.13,14

Benefits

  • Methylcobalamin is the active form of vitamin B12 for maximum benefit
  • Superior bioavailability to the more common form, cyanocobalamin, which does not convert to enough methylcobalamin to correct some forms of anemia, neurological defects, and aging1
  • Lowers homocysteine levels for protective cardiovascular benefits
  • Sublingual tablets allow for fast acting delivery system directly into blood stream

Medicinal Ingredients

Each Tablet Contains:
Vitamin B12 (Methylcobalamin) 5000 mcg

Non-Medicinal Ingredients

Lactose monohydrate, microcrystalline cellulose, croscarmellose sodium, vegetable grade magnesium stearate (lubricant).

Dosage

Recommended Adult Dose: 1 tablet per day or as directed by a health care practitioner. Dissolve under the tongue. Consult a health care practitioner for use beyond 4 months.

Allergens

Contains no artificial colours, preservatives, or sweeteners; no starch, sugar, wheat, gluten, yeast, soy, corn, egg, fish, shellfish, salt, tree nuts, or GMOs. Suitable for vegetarians. Sealed for your protection. Do not use if seal is broken. For freshness, store in a cool, dry place.

Contraindications

Consult a health care practitioner prior to use if you are pregnant or breastfeeding. High doses in oncology patients may be cautioned against because of its role in DNA synthesis. Supplemental folic acid may mask a B12 deficiency, which should be ruled out. Folic acid, as well as increased potassium intake, is recommended with B12 therapy. Keep out of reach of children.

Drug Interactions

Although several classes of drugs, such as aminoglycosides, anticonvulsants, bile acid sequestrants, and proton pump inhibitors are known to interfere with B12 absorption or function, there are no known negative interactions caused by B12 supplementation with any medications.16-22 B12 may enhance the function or reduce the adverse effects of several medication classes, such as SSRIs and oral contraceptives.23

Legal Disclaimer

* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

The product information on this website may not be 100% accurate. Please ensure to check the product packaging information before consumption, especially if you have allergies or other health conditions.

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