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Combination of TMG Trimethylglycine, Vitamin B6 P5P, Vitamin B12 Methylcobalamin and Folic Acid

Methylation Support Supplement and Co-Factors

MaxMethyl contains all the cofactors and methyl donors needed to promote methylation: vitamin B6, vitamin B12, folate and trimethylglycine (TMG).

Methylation is a key process that is essential for the function of every cell in the body, keeping aging and disease at bay.

Recently it was discovered that a large portion of the population has a mutation of the gene MTHFR, which prevents them from converting folate into its usable form, L-5-MTHF.  This leads to folate deficiency and decreased methylation, resulting in high homocysteine levels. The folate used in MaxMethyl is in the form of L-5-MTHF, which makes it an ideal supplement for those with the MTHFR mutation.


  • Optimal Methylation: Our cutting-edge formula combines Methyl B12 and Methyl Folate, ensuring your body receives the essential nutrients for efficient methylation, the cornerstone of detoxification and overall well-being.
  • Cardiovascular Wellness: Boost your cardiovascular health with our Methyl B12 Folate blend. These vital vitamins support healthy blood flow and help maintain optimal heart function, keeping you in top shape.
  • Enhanced Brain Power: Experience improved cognitive function with Vitamin B6 (P5P) and Vitamin B12 (Methylcobalamin B12), known to support mental clarity and focus.
  • Serotonin Balance: Our 5-HTP with Vitamin B6 formula promotes a positive mood and better sleep, helping you feel your best every day.
  • Detoxify Naturally: Trimethylglycine (TMG) in our supplement aids in detoxification, ensuring your body rids itself of harmful toxins, while Folic Acid supplements your overall nutritional needs.
  • NPN 80026949


Most people do not get enough of the specific nutrients that support methylation in their diets. AOR’s MaxMethyl is formulated to include all the cofactors and methyl donors needed.

Supplement Facts

Vitamin B6 (pyridoxal-5-phosphate) 

17 mg
Folic acid (calcium L-5-MTHF)
267 mcg
Vitamin B12 (methylcobalamin)
216 mcg
Trimethylglycine (betaine anhydrous)
500 mg

Non-medicinal Ingredients

none. Capsule: hypromellose.

*NMIs are subject to change. Always read and follow the label for accurate ingredient and allergen information.

Recommended Dose

Take one capsule three times daily with or without food, or as directed by a qualified health care practitioner.

Main Applications

  • Methylation
  • Detoxification


MaxMethyl provides nutrients that help in the formation of tissue and red blood cells, and in the metabolism of carbohydrates, fats, and proteins.


AOR™ guarantees that all ingredients have been declared on the label. Contains no wheat, gluten, corn, nuts, peanuts, sesame seeds, sulphites, mustard, soy, dairy, eggs, fish, shellfish or any animal by-product.


Consult a health care practitioner prior to use if you are pregnant, breastfeeding, or if you have liver or cardiovascular disease.


The information and product descriptions appearing on this website are for information purposes only, and are not intended to provide or replace medical advice to individuals from a qualified health care professional. Consult with your physician if you have any health concerns, and before initiating any new diet, exercise, supplement, or other lifestyle changes.

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