Berber 500mg | Cytomatrix® | 60 Vegetable Capsules


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500mg of pure Berberis aquifolium

Standardized to 97% berberine content

To support  powerful anti-microbial action

Digestive support & blood sugar control

Berberine is a plant alkaloid that possesses a number of powerful medicinal properties. It has traditionally been delivered as the active ingredient in goldenseal, Oregon grape and barberry extracts to provide broad-spectrum antimicrobial actions and digestive support. However, more recently its isolation and powerful application for blood sugar control, insulin resistance and cholesterol management have become evident.


  • Indicated as a broad-spectrum antimicrobial agent, digestive support aid and protective agent against blood sugar dysregulation and insulin resistance
  • 500mg of Berberis aquifolium in each vegetable capsule, standardized to 97% berberine content
  • NPN: 80099275
  • Vegan. GMO, gluten, soy and dairy free.

When it comes to berberine’s antimicrobial actions, research has found that it effectively combats bacteria, viruses, fungi and parasites. It achieves these antimicrobial actions through multiple mechanisms including the inhibition of microbial growth, endotoxin formation, bacterial adhesion and viral replication. This allows for a truly broad-spectrum approach for patients with dysbiosis, chronic infections or exposure to multiple pathogenic microbes.

Berberine has a particularly affinity and beneficial action in the digestive tract. Evidence has shown that berberine can effectively treat symptoms of bacterial diarrhea and intestinal parasites. In addition, berberine can improve the integrity of tight junctions in the digestive tract and, therefore, positively affect intestinal permeability. Finally, berberine can regulate gastrointestinal motility and increase the gut production of butyrate, a shortchain fatty acid that provides fuel and anti-inflammatory support in the colon.

Regarding metabolic function, research has uncovered the vast application of berberine for insulin and blood sugar regulation. Double-blinded, placebo-controlled studies using berberine in those with existing medical conditions have found that it can reduce fasting blood sugar levels, insulin resistance, hemoglobin A1c, triglycerides, total cholesterol and LDL measures. Remarkably, these effects are considered comparable to oral hypoglycemic medications. Individuals with non alcoholic fatty liver have also seen comparable improvements in lipids, body mass index and insulin resistance, with significant improvements in liver fat content.

Cyto-Matrix’s Berber contains 500mg of Berberis aquifolium (Oregon grape extract) per capsule, standardized to 97% berberine content to provide therapeutic support for healthy digestion, microbial balance, blood sugar regulation and metabolic control.



Ingredient Amount
Oregon Grape extract
root, Berberis aquifolium

Unit of Measure above: Each capsule

Non-Medicinal Ingredients

Vegetable-grade magnesium stearate, silicon dioxide, microcrystalline cellulose. Capsule: hypromellose.



Adults - Take 1 capsule, 2 times per day at the beginning of each meal or as directed by a healthcare professional.

Duration of Use

For use beyond 3 months, consult a healthcare professional.


Provides support for healthy glucose metabolism and healthy cholesterol levels (serum triglyceride, total, and LDL). Helps to support cardiovascular health.


Do not use if safety seal is broken. Consult a healthcare professional prior to use, especially if you have diabetes, gall stones, hypoglycemia or hypotension, liver disorder or cardiovascular disease. Consult a healthcare professional if you are taking other medication or natural health product as berberine is known to affect the metabolism of numerous drug. If you experience symptoms of hypoglycemia such as feelings of anxiety, dizziness, tremor, sweating, nausea, headache, paleness, chills, confusion, discontinue use and consult a healthcare professional.


Do not use if you are pregnant or breastfeeding.

Known Adverse Reactions

May cause gastrointestinal irritation such as constipation, vomiting, abdominal pain or diarrhea, in which case, discontinue use and consult a healthcare professional.

Legal Disclaimer 

* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

The product information on this website may not be 100% accurate. Please ensure to check the product packaging information before consumption, especially if you have allergies or other health conditions.

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