Description
Cardiovascular Support
CoQ10 is commonly called ubiquinone because it is ubiquitous throughout the body and found in nearly every cell. The active form of the molecule, ubiquinol, is a fat-soluble antioxidant that protects fats such as those that make up cellular and mitochondrial membranes, as well as both HDL and LDL cholesterol. However, CoQ10’s most important role is in cellular respiration, the process of generating the energy (ATP) that all cells need for optimal health.1,2,3
Because its role in energy production is so critical, it is particularly important in cells with high energy demands, such as the heart. This helps explain why CoQ10 has shown such significant benefit for conditions affecting the cardiovascular system, such as high blood pressure, cardiomyopathy, protection during cardiac surgery, and protection from statin drugs used to treat high cholesterol. Low levels of CoQ10 have also been reported for many other conditions, with clinical trials supporting the use of CoQ10 for migraine headaches, male infertility, Alzheimer’s (prevention) and Parkinson’s disease (prevention and treatment), and macular degeneration.4,5,6,7,8,9,10 Moderate doses, ranging from 300–600 mg per day, have been used for statin-related myopathy, female infertility (decreased ovarian reserve), and multiple sclerosis.11,12,13
Kaneka Q+ ubiquinol provides the form of CoQ10 found in 95% of human tissues. Higher levels of ubiquinol compared to ubiquinone are a sign of better cellular protection.14 Kaneka Q+ ubiquinol has also been shown to be more soluble than ubiquinone, more effectively increasing blood levels of this nutrient so critical to energy production.15,16,17 A base of organic flaxseed oil improves the solubility of ubiquinol and provides heart-healthy omega-3 fatty acids. Flaxseed oil is especially rich in alpha-linolenic acid, an anti-inflammatory oil associated with improved cardiovascular health.18
Features
- Offers a highly absorbable and bioavailable form of CoQ10
- Increases plasma levels of CoQ10 significantly more per mg compared to ubiquinone
- Allows for higher peak plasma levels of CoQ10, with 200 mg per softgel reflective of clinical trial dosing
- Kaneka Q+ brand for ubiquinol is naturally produced via yeast fermentation and is free of the impurities of synthetically processed CoQ10
- A base of organic flaxseed oil improves solubility and provides ALA-rich omega-3 fatty acids
- Genetically modified organism (GMO) free, allergen free, and Kosher certified
Ingredients
| Each softgel Contains : | |
| Ubiquinol (Kaneka QH® Ubiquinol (Microorganism) (Bioactive and Reduced Form of CoQ10) | 200 mg |
| Organic Flaxseed Oil (Linum usitatissimum) (seed) | 340 mg |
Non-medicinal Ingredients
Softgel (gelatin, glycerin, purified water, carob), yellow beeswax, non-GMO sunflower lecithin, natural vitamin E.
Purity
Contains no artificial colours, preservatives, or sweeteners; no dairy, starch, sugar, wheat, gluten, yeast, soy, corn, egg, fish, shellfish, salt, tree nuts, or GMOs. Sealed for your protection. Do not use if seal is broken. For freshness, store in a cool, dry place.
Dosage
Recommended Adult Dose: 1 softgel per day or as directed by a health care practitioner.
Contraindications
No significant contraindications.
Drug Interactions
Although existing evidence has not found an interaction, CoQ10 resembles vitamin K structurally, potentially interfering with the anticoagulant warfarin. Close monitoring of the INR is recommended with CoQ10 introduction in these patients. No other negative drug interactions are known for CoQ10, though a number of medications are thought to interfere with CoQ10 synthesis or function in the body, including statin medications, tricyclic antidepressants, and oral hypoglycemic agents.19
Cautions & Warnings
- Consult a health care practitioner prior to use if you are taking blood pressure medication or blood thinners, or if you are pregnant or breastfeeding.
- Keep out of reach of children.
- Although existing evidence has not found an interaction, CoQ10 resembles vitamin K structurally, potentially interfering with blood thinners, antiplatelets, or anticoagulants.
- Close monitoring of the INR is recommended with CoQ10 introduction in these patients.
- No other negative drug interactions are known for CoQ10, though a number of medications are thought to interfere with CoQ10 synthesis or function in the body, including statin medications, tricyclic antidepressants and oral hypoglycemic agents.
