DIM® Enhanced | Douglas Laboratories | 30 Veggie Caps



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Microencapsulated DIM with Meriva® curcumin, green tea, and Wasabia japonica

Estrogen metabolism and antioxidant support 

DIM® Enhanced is a microencapsulated form of diindolylmethane (DIM) designed to promote healthy estrogen balance. Curcuminoids and green tea extract are also included alongside wasabi.


  • Helps to support/promote healthy estrogen metabolism/balance
  • Helps reduce the severity and duration of symptoms associated with recurrent breast pain (cylical mastalgia)
  • Source of/provides antioxidants.
  • Estrogen metabolism
  • Recurrent breast pain (cyclical mastalgia)
  • Natural
  • Non-GMO
  • Gluten-Free
  • NPN: 80064554

Healthy hormone detoxification is a crucial part of the normal functioning of organs, including the breast. DIM is known to help stimulate natural detoxification enzymes to support healthy estrogen metabolism. As a natural component derived from indole-3-carbine and cruciferous vegetables, DIM has been shown in clinical research to favour the production of the estrogen metabolite 2-hydroxysteroid over the more deleterious 16-hydroxyestrone. DIM can also decrease the severity and duration of recurrent breast pain and promote antioxidant support. Microencapsulated DIM® by BioResponse® is a patented, absorption-enhancing formulation to ensure proper assimilation by the body. It is the only DIM with proven absorption and activity demonstrated in independently performed clinical studies.

Polyphenols in green tea, specifically catechins, provide the primary health-promoting benefits associated with green tea consumption. Catechins, most notably epigallocatechin gallate (EGCG), are effective antioxidants and decrease harmful oxidative damage. Similarly, curcuminoids are naturally occurring bioactive compounds from turmeric. Since curcuminoids exhibit poor absorption when consumed orally, DIM® Enhanced contains a highly bioavailable curcumin complex called MERIVA. Pharmacokinetic comparison studies have shown MERIVA to have up to a 20-fold improvement in bioavailability versus the standard 95% turmeric extracts.

Wasabia japonica (a member of the cruciferous vegetable family) contains long chain isothiocyanates (ITCs), which are unique to wasabia.


Each Capsule Contains:
Bioresponse DIM:DIM (3,3'-Methylenebis-1H-indole)
125 mg 
3,3'-Diindolylmethane/ 3,3'-Diindolylméthane
31.25 mg
Green Tea Leaf Extract/ Extrait de feuille de thé vert
(Camellia sinensis) (20:1) (4000 mg dried equivalent/
équivalent sec; 45% EGCG)
 200 mg
125 mg 
Curcuminoids (from Curcuma longa rhizome)/
25 mg 
Wasabi Rhizome/ Rhizome de wasabi (Wasabia japonica)
50 mg

Non-medicinal Ingredients

Hypromellose (capsule), Cellulose, Silica, Magnesium Stearate, Dibasic calcium phosphate dihydrate, Starch , Vitamin E, phosphatidylcholine (from sunflower).

Suggested Usage

Adults: Take 1 capsule 2 times daily with meals or as directed by your healthcare practitioner.

Consult your healthcare practitioner for use beyond 12 weeks.


Consult a health care practitioner prior to use if you are taking any medical treatment or natural health products, if you have a liver disorder or symptoms of low estrogen (such as joint pain, mood changes, hot flashes, night sweats, vaginal dryness or irregular menstruations), if you have an iron deficiency, if you have gallstones or a bile duct obstruction, if you have stomach ulcers or excess stomach acid, or if you are attempting to conceive. To exclude the diagnosis of a serious cause of hormonal imbalance, consult a health care practitioner prior to use. If you develop symptoms of liver trouble (such as abdominal pain, dark urine or jaundice) or symptoms of low estrogen, discontinue use and consult a health care practitioner. Do not use if you are pregnant or breastfeeding. Store in a cool, dry place, away from direct light. Keep out of reach of children

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