Description
Methylation Factors (Optimize methylation)
Active folate (5-MTHF) with Vitamins B2, B6, and B12
Supports methylation and Healthy Level of homocysteine
Support cellular energy production, heart health, brain function, and mood with nutrients
Methyl-Guard Plus provides superior methyl donors – trimethylglycine, 5-MTHF, and methylcobalamin – combined with bioactive vitamins B2 and B6 in a powerhouse formula for whole-body methylation support.
Features
- Healthy Methylation: Methyl-Guard Plus supports methylation and promotes a healthy level of homocysteine
- Active Forms: Formulated with active folate (5-MTHF) and the active, tissue-ready forms of vitamins B2, B6, and B12 to optimize absorption
- Free From: Doesn't contain gluten, eggs, tree nuts, peanuts, dairy, soy, fish, or shellfish
- Trusted: Thorne is chosen by champions and trusted by 100+ pro teams. Thorne is the only supplement manufacturer to collaborate with Mayo Clinic on wellness research and content. Thorne is also a proud partner of 11 U.S. Olympic Teams
- Methylation Factors
- Dietary Supplement
- Heart / Vessels / Mood
- Gluten-Free, Dairy-Free, Soy-Free
- NPN: 80061614
Various conditions and stressors can have an adverse impact on the body’s methylation cycle. Nutrient deficiencies, environmental exposures, and other aspects of a modern lifestyle can cause inefficient methylation. In addition, approximately 60 percent of U.S. adults have a genetic variation that makes it difficult for their methylation cycle to function optimally.
Thorne’s Methyl-Guard Plus features betaine (trimethylgycine), methylated vitamin B12 (methylcobalamin) and folate (5-MTHF), as well as the active forms of vitamins B2 and B6, for providing efficient nutritional support for the body’s methylation challenges.
Benefits of Thorne’s Methyl-Guard Plus:
Nutritional support for individuals who have MTHFR gene mutations.
Enhanced cellular energy production fights fatigue.
Helps maintain a healthy homocysteine level in the blood, which supports cardiovascular, cognitive, and bone health.
Promotes fat metabolism and lean body composition.
Supports neurotransmitter production – natural chemicals that play an important role in nervous system functions, like attention, focus, mood, and sleep.
Promotes liver detoxification of many substances, including hormones like estrogen.
Why is methylation important:
Methylation is a simple reaction where a small molecule known as a “methyl group” is transferred from one substance to another. Methylation significantly impacts many biochemical reactions in the body and plays a beneficial role in:
Cardiovascular health
Cellular energy production
Fat metabolism
Neurological function
DNA production
Liver detoxification processes
Eye health
Histamine balance
Who can benefit from Methyl-Guard Plus:
Individuals with mutations to MTHFR and other genes that adversely affect methylation.
Aging individuals wanting to support their cardiovascular, cognitive, and metabolic health.
Women seeking support for estrogen metabolism and bone health.
Individuals wanting nutritional support for fat metabolism and maintenance of a healthy body composition.
Anyone with limited consumption of methylation-supportive foods like green leafy vegetables, legumes, and cruciferous vegetables.
Features of Methyl-Guard Plus:
Betaine, also known as trimethylglycine, is a superior methyl donor
The methylated forms of vitamin B12 (methylcobalamin) and folate (5-MTHF) benefit individuals with certain gene mutations.
Active forms of vitamins B2 and B6 – key cofactors in methylation processes
B vitamins in their active, tissue-ready forms means your body gets the greatest benefit with the least additional work.
Robust methylation support in fewer capsules per day than Thorne’s original Methyl-Guard.
Medicinal Ingredients
| Name | Amount |
|---|---|
| Betaine Anhydrous (Trimethylglycine) | 1.8g |
| Folate (L-5-MTHF) | 5mg DFE |
| Vitamin B12 (Methylcobalamin) | 3mg |
| Vitamin B2 (Riboflavin 5'-Phosphate Sodium) | 90mg |
| Vitamin B6 (Pyridoxal 5'-Phosphate) | 45mg |
Non-Medicinal Ingredients
Calcium (Citrate), Calcium Laurate, Hypromellose Capsule
Recommended Dose
Take 1-3 capsules daily or as recommended by your health professional.
Cautions
ALLERGY WARNING
This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients.
PREGNANCY
If pregnant, consult your health professional before using this product.
INTERACTIONS
5-methyltetrahydrofolate (5-MTHF) supplementation is not recommended concurrently with methotrexate cancer therapy, as it can interfere with methotrexate's anti-neoplastic activity; however, 5-MTHF has not been shown to interfere with the anti-inflammatory activity of methotrexate. An individual taking methotrexate for psoriasis or rheumatoid arthritis can safely take a supplement containing folate.
Legal Disclaimer
Usage: Use this product as directed on the label. Do not exceed the recommended dosage.
Consultation: Consult with a healthcare professional before use, especially if you are pregnant, nursing, have a medical condition, or are taking any medications.
Safety: Keep out of reach of children. In case of accidental overdose, seek professional assistance or contact a poison control center immediately.
Import Regulations: It is the responsibility of the consumer to ensure that this product complies with all local regulations and import requirements before purchasing and consuming this product.
Storage: Store in a cool, dry place, away from direct sunlight and heat.
By purchasing and using this product, you acknowledge and accept the terms of this disclaimer.
For any questions or concerns regarding this product, please contact our customer service team.
